Microscale Contacting of Two Immiscible Liquid Droplets to Measure Interfacial TensionSHIBATA, Yuichi; YANAI, Takehiko; OKAMOTO, Osamu et al.Heat transfer engineering. 2013, Vol 34, Num 1-3, pp 113-119, issn 0145-7632, 7 p.Conference Paper

Heat stroke burn: unusual cutaneous damage due to heat waveNAKAMURA, Yusuke; TAKEO, Naoko; KUBO, Takeshi et al.EJD. European journal of dermatology. 2014, Vol 24, Num 1, pp 115-116, issn 1167-1122, 2 p.Article

2-Cyclohexylcarbonylbenzimidazoles as potent, orally available and brain-penetrable opioid receptor-like 1 (ORL1) antagonistsKOBAYASHI, Kensuke; UCHIYAMA, Minaho; ASAI, Masanori et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 11, pp 3096-3099, issn 0960-894X, 4 p.Article

A Novel Class of Cycloalkano[b]pyridines as Potent and Orally Active Opioid Receptor-like 1 Antagonists with Minimal Binding Affinity to the hERG K⁺ ChannelYOSHIZUMI, Takashi; TAKAHASHI, Hirobumi; AZUMA-KANOH, Tomoko et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 13, pp 4021-4029, issn 0022-2623, 9 p.Article

A novel point mutation in type III collagen gene resulting in exon 24 skipping in a case of vascular type Ehlers-Danlos syndromeOKAMOTO, Osamu; ANDO, Tadasuke; WATANABE, Atsushi et al.Archives of dermatological research (Print). 2008, Vol 300, Num 9, pp 525-529, issn 0340-3696, 5 p.Article

Identification of novel benzimidazole series of potent and selective ORL1 antagonistsOKAMOTO, Osamu; KOBAYASHI, Kensuke; SAKOH, Hiroki et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 11, pp 3278-3281, issn 0960-894X, 4 p.Article

Discovery of substituted 2,4,4-triarylimidazoline derivatives as potent and selective neuropeptide Y Y5 receptor antagonistsSATO, Nagaaki; JITSUOKA, Makoto; KANATANI, Akio et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 6, pp 1670-1674, issn 0960-894X, 5 p.Article

Synthesis and biological evaluation of imidazole derivatives as novel NOP/ORL1 receptor antagonists: Exploration and optimization of alternative pyrazole structureSUGIMOTO, Yuichi; KOBAYASHI, Kensuke; ASAI, Masanori et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 16, pp 4611-4616, issn 0960-894X, 6 p.Article

Design, synthesis, and biological evaluation of indole derivatives as novel nociceptin/orphanin FQ Nn/OFQ receptor antagonistsSUGIMOTO, Yuichi; SHIMIZU, Atsushi; KATO, Tetsuya et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 13, pp 3569-3573, issn 0960-894X, 5 p.Article

Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and LFALGUEYRET, Jean-Pierre; OBALLA, Renata M; OKAMOTO, Osamu et al.Journal of medicinal chemistry (Print). 2001, Vol 44, Num 1, pp 94-104, issn 0022-2623Article

Identification of MK-1925: A selective, orally active and brain-penetrable opioid receptor-like 1 (ORL1) antagonistKOBAYASHI, Kensuke; TSUJITA, Tomohiro; OKAMOTO, Osamu et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 16, pp 4729-4732, issn 0960-894X, 4 p.Article

Optimization of benzimidazole series as opioid receptor-like 1 (ORL1) antagonists: SAR study directed toward improvement of selectivity over hERG activityKOBAYASHI, Kensulce; KATO, Tetsuya; OZAKI, Satoshi et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 11, pp 3100-3103, issn 0960-894X, 4 p.Article

Identification of an Orally Active Opioid Receptor-like 1 (ORL1) Receptor Antagonist 4-{3-[(2R)-2,3-Dihydroxypropyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}-1-[(1S,3S,4R)-spiro[bicyclo[2.2.1]heptane-2,1'-cyclopropan]-3-ylmethyl]piperidine as Clinical CandidateSATOH, Atsushi; SAGARA, Takeshi; OKUDA, Shoki et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 14, pp 4091-4094, issn 0022-2623, 4 p.Article

Novel ORL1-selective antagonists with oral bioavailability and brain penetrabilityOKAMOTO, Osamu; KOBAYASHI, Kensuke; OZAKI, Satoshi et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 11, pp 3282-3285, issn 0960-894X, 4 p.Article

Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarityGOTO, Yasuhiro; ARAI-OTSUKI, Sachie; SAGARA, Takeshi et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 3, pp 847-849, issn 0022-2623, 3 p.Article